diff --git a/doc/api/index.rst b/doc/api/index.rst
index 3656bba286e..5c4c4cc0ed6 100644
--- a/doc/api/index.rst
+++ b/doc/api/index.rst
@@ -213,6 +213,7 @@ Class-style Parameters
     :template: autosummary/params.rst
 
     Box
+    Frame
     Pattern
 
 Enums
diff --git a/pygmt/params/__init__.py b/pygmt/params/__init__.py
index b80b921407a..12a788e3352 100644
--- a/pygmt/params/__init__.py
+++ b/pygmt/params/__init__.py
@@ -3,4 +3,5 @@
 """
 
 from pygmt.params.box import Box
+from pygmt.params.frame import Axes, Axis, Frame
 from pygmt.params.pattern import Pattern
diff --git a/pygmt/params/frame.py b/pygmt/params/frame.py
new file mode 100644
index 00000000000..6c4c2969cfa
--- /dev/null
+++ b/pygmt/params/frame.py
@@ -0,0 +1,139 @@
+"""
+The Axes, Axis, and Frame classes for specifying the frame.
+"""
+
+import dataclasses
+from typing import Any, Literal
+
+from pygmt.alias import Alias
+from pygmt.params.base import BaseParam
+
+
+@dataclasses.dataclass(repr=False)
+class Axis(BaseParam):
+    """
+    Class for setting up one axis of a plot.
+    """
+
+    #: Intervals for annotations and major tick spacing, minor tick spacing, and/or
+    #: grid line spacing.
+    interval: float | str
+
+    #: Plot slanted annotations (for Cartesian plots only), where *angle* is measured
+    #: with respect to the horizontal and must be in the -90 <= *angle* <= 90 range.
+    #: Default is normal (i.e., ``angle=90``) for y-axis and parallel (i.e.,
+    #: ``angle=0``) for x-axis annotations. These defaults can be changed via
+    #: :gmt-term:`MAP_ANNOT_ORTHO`.
+    angle: float | None = None
+
+    #: Skip annotations that fall exactly at the ends of the axis. Choose from ``left``
+    #: or ``right`` to skip only the lower or upper annotation, respectively, or
+    #: ``True`` to skip both.
+    skip_edge: Literal["left", "right"] | bool = False
+
+    #: Give fancy annotations with W|E|S|N suffixes encoding the sign (for geographic
+    #: axes only).
+    fancy: bool = False
+
+    #: Add a label to the axis (for Cartesian plots only). The label is placed parallel
+    #: to the axis by default; use **hlabel** to force a horizontal label for y-axis,
+    #: which is useful for very short labels.
+    label: str | None = None
+    hlabel: str | None = None
+
+    #: Add an alternate label for the right or upper axes. The label is placed parallel
+    #: to the axis by default; use **alt_hlabel** to force a horizontal label for
+    #: y-axis, which is useful for very short labels. [For Cartesian plots only].
+    alt_label: str | None = None
+    alt_hlabel: str | None = None
+
+    #: Add a leading text prefix for axis annotation (e.g., dollar sign for plots
+    #: related to money) (for Cartesian plots only). For geographic maps the addition
+    #: of degree symbols, etc. is automatic and controlled by
+    #: :gmt-term:`FORMAT_GEO_MAP`.
+    prefix: str | None = None
+
+    #: Append a unit to the annotations (for Cartesian plots only). For geographic maps
+    #: the addition of degree symbols, etc. is automatic and controlled by
+    #: :gmt-term:`FORMAT_GEO_MAP`.
+    unit: str | None = None
+
+    @property
+    def _aliases(self):
+        return [
+            Alias(self.interval, name="interval"),
+            Alias(self.angle, name="angle", prefix="+a"),
+            Alias(
+                self.skip_edge,
+                name="skip_edge",
+                prefix="+e",
+                mapping={True: True, "left": "l", "right": "r"},
+            ),
+            Alias(self.fancy, name="fancy", prefix="+f"),
+            Alias(self.label, name="label", prefix="+l"),
+            Alias(self.hlabel, name="hlabel", prefix="+L"),
+            Alias(self.alt_label, name="alt_label", prefix="+s"),
+            Alias(self.alt_hlabel, name="alt_hlabel", prefix="+S"),
+            Alias(self.unit, name="unit", prefix="+u"),
+        ]
+
+
+@dataclasses.dataclass(repr=False)
+class Axes(BaseParam):
+    """
+    Class for specifying the frame of a plot.
+    """
+
+    #: Specify which axes to draw and their attributes.
+    axes: str | None = None
+
+    #: Fill for the interior of the canvas [Default is no fill]. This also sets fill
+    #: for the two back-walls in 3-D plots.
+    fill: str | None = None
+
+    #: The title string centered above the plot frame [Default is no title].
+    title: str | None = None
+
+    #: The subtitle string beneath the title [Default is no subtitle]. This requires
+    #: ``title`` to be set.
+    subtitle: str | None = None
+
+    @property
+    def _aliases(self):
+        return [
+            Alias(self.axes, name="axes"),
+            Alias(self.fill, name="fill", prefix="+g"),
+            Alias(self.title, name="title", prefix="+t"),
+            Alias(self.subtitle, name="subtitle", prefix="+s"),
+        ]
+
+
+@dataclasses.dataclass(repr=False)
+class Frame(BaseParam):
+    """
+    Class for setting up the frame of a plot.
+    """
+
+    axes: Any = None
+    xaxis: Any = None
+    yaxis: Any = None
+    zaxis: Any = None
+
+    @property
+    def _aliases(self):
+        return [
+            Alias(self.axes),
+            Alias(self.xaxis, prefix="x"),
+            Alias(self.yaxis, prefix="y"),
+            Alias(self.zaxis, prefix="z"),
+        ]
+
+    def __iter__(self):
+        """
+        Iterate over the aliases of the class.
+
+        Yields
+        ------
+        The value of each alias in the class. None are excluded.
+        """
+        yield from (alias._value for alias in self._aliases if alias._value is not None)
diff --git a/pygmt/tests/test_params_frame.py b/pygmt/tests/test_params_frame.py
new file mode 100644
index 00000000000..85de1bb406b
--- /dev/null
+++ b/pygmt/tests/test_params_frame.py
@@ -0,0 +1,30 @@
+"""
+Test the Frame/Axes/Axis classes.
+"""
+
+from pygmt.params import Axes, Axis
+
+
+def test_params_axis():
+    """
+    Test the Axis class.
+    """
+    assert str(Axis(interval="a1f0.5")) == "a1f0.5"
+    assert str(Axis(interval="a1f0.5", angle=30)) == "a1f0.5+a30"
+    assert str(Axis(interval="a1f0.5", angle=30, skip_edge="left")) == "a1f0.5+a30+el"
+    assert str(Axis(interval="a1f0.5", fancy=True)) == "a1f0.5+f"
+    assert str(Axis(interval="a1f0.5", label="My Label")) == "a1f0.5+lMy Label"
+    assert str(Axis(interval="a1f0.5", hlabel="My HLabel")) == "a1f0.5+LMy HLabel"
+    assert str(Axis(interval="a1f0.5", alt_label="Alt Label")) == "a1f0.5+sAlt Label"
+    assert str(Axis(interval="a1f0.5", alt_hlabel="Alt HLabel")) == "a1f0.5+SAlt HLabel"
+    assert str(Axis(interval="a1f0.5", unit="km")) == "a1f0.5+ukm"
+
+
+def test_params_axes():
+    """
+    Test the Axes class.
+    """
+    assert (
+        str(Axes("WSen", title="My Plot Title", fill="lightred"))
+        == "WSen+glightred+tMy Plot Title"
+    )