diff --git a/newsfragments/5552.added.md b/newsfragments/5552.added.md
new file mode 100644
index 00000000000..e0d1380090f
--- /dev/null
+++ b/newsfragments/5552.added.md
@@ -0,0 +1 @@
+Introspection: `@typing.final` on final classes
\ No newline at end of file
diff --git a/pyo3-introspection/src/introspection.rs b/pyo3-introspection/src/introspection.rs
index 706ac870f8e..42789941660 100644
--- a/pyo3-introspection/src/introspection.rs
+++ b/pyo3-introspection/src/introspection.rs
@@ -124,9 +124,17 @@ fn convert_members<'a>(
                     chunks_by_parent,
                 )?);
             }
-            Chunk::Class { name, id } => {
-                classes.push(convert_class(id, name, chunks_by_id, chunks_by_parent)?)
-            }
+            Chunk::Class {
+                name,
+                id,
+                decorators,
+            } => classes.push(convert_class(
+                id,
+                name,
+                decorators,
+                chunks_by_id,
+                chunks_by_parent,
+            )?),
             Chunk::Function {
                 name,
                 id: _,
@@ -178,6 +186,7 @@ fn convert_members<'a>(
 fn convert_class(
     id: &str,
     name: &str,
+    decorators: &[ChunkTypeHint],
     chunks_by_id: &HashMap<&str, &Chunk>,
     chunks_by_parent: &HashMap<&str, Vec<&Chunk>>,
 ) -> Result<Class> {
@@ -198,9 +207,29 @@ fn convert_class(
         name: name.into(),
         methods,
         attributes,
+        decorators: decorators
+            .iter()
+            .map(convert_decorator)
+            .collect::<Result<_>>()?,
     })
 }
 
+fn convert_decorator(decorator: &ChunkTypeHint) -> Result<PythonIdentifier> {
+    match convert_type_hint(decorator) {
+        TypeHint::Plain(id) => Ok(PythonIdentifier {
+            module: None,
+            name: id.clone(),
+        }),
+        TypeHint::Ast(expr) => {
+            if let TypeHintExpr::Identifier(i) = expr {
+                Ok(i)
+            } else {
+                bail!("PyO3 introspection currently only support decorators that are identifiers of a Python function")
+            }
+        }
+    }
+}
+
 fn convert_function(
     name: &str,
     arguments: &ChunkArguments,
@@ -211,19 +240,7 @@ fn convert_function(
         name: name.into(),
         decorators: decorators
             .iter()
-            .map(|d| match convert_type_hint(d) {
-                TypeHint::Plain(id) => Ok(PythonIdentifier {
-                    module: None,
-                    name: id.clone(),
-                }),
-                TypeHint::Ast(expr) => {
-                    if let TypeHintExpr::Identifier(i) = expr {
-                        Ok(i)
-                    } else {
-                        bail!("A decorator must be the identifier of a Python function")
-                    }
-                }
-            })
+            .map(convert_decorator)
             .collect::<Result<_>>()?,
         arguments: Arguments {
             positional_only_arguments: arguments.posonlyargs.iter().map(convert_argument).collect(),
@@ -444,6 +461,8 @@ enum Chunk {
     Class {
         id: String,
         name: String,
+        #[serde(default)]
+        decorators: Vec<ChunkTypeHint>,
     },
     Function {
         #[serde(default)]
diff --git a/pyo3-introspection/src/model.rs b/pyo3-introspection/src/model.rs
index d6fdd8945ee..e747b5c3e52 100644
--- a/pyo3-introspection/src/model.rs
+++ b/pyo3-introspection/src/model.rs
@@ -13,6 +13,8 @@ pub struct Class {
     pub name: String,
     pub methods: Vec<Function>,
     pub attributes: Vec<Attribute>,
+    /// decorator like 'typing.final'
+    pub decorators: Vec<PythonIdentifier>,
 }
 
 #[derive(Debug, Eq, PartialEq, Clone, Hash)]
diff --git a/pyo3-introspection/src/stubs.rs b/pyo3-introspection/src/stubs.rs
index 7181a02ab18..11f8c25a848 100644
--- a/pyo3-introspection/src/stubs.rs
+++ b/pyo3-introspection/src/stubs.rs
@@ -119,7 +119,15 @@ fn module_stubs(module: &Module, parents: &[&str]) -> String {
 }
 
 fn class_stubs(class: &Class, imports: &Imports) -> String {
-    let mut buffer = format!("class {}:", class.name);
+    let mut buffer = String::new();
+    for decorator in &class.decorators {
+        buffer.push('@');
+        imports.serialize_identifier(decorator, &mut buffer);
+        buffer.push('\n');
+    }
+    buffer.push_str("class ");
+    buffer.push_str(&class.name);
+    buffer.push(':');
     if class.methods.is_empty() && class.attributes.is_empty() {
         buffer.push_str(" ...");
         return buffer;
@@ -433,6 +441,9 @@ impl ElementsUsedInAnnotations {
     }
 
     fn walk_class(&mut self, class: &Class) {
+        for decorator in &class.decorators {
+            self.walk_identifier(decorator);
+        }
         for method in &class.methods {
             self.walk_function(method);
         }
@@ -658,6 +669,10 @@ mod tests {
                     name: "A".into(),
                     methods: Vec::new(),
                     attributes: Vec::new(),
+                    decorators: vec![PythonIdentifier {
+                        module: Some("typing".into()),
+                        name: "final".into(),
+                    }],
                 }],
                 functions: vec![Function {
                     name: String::new(),
@@ -683,6 +698,7 @@ mod tests {
                 "from bat import A as A2",
                 "from builtins import int as int2",
                 "from foo import A as A3, B",
+                "from typing import final"
             ]
         );
         let mut output = String::new();
diff --git a/pyo3-macros-backend/src/introspection.rs b/pyo3-macros-backend/src/introspection.rs
index bab266b960b..deac4c807d2 100644
--- a/pyo3-macros-backend/src/introspection.rs
+++ b/pyo3-macros-backend/src/introspection.rs
@@ -89,19 +89,26 @@ pub fn class_introspection_code(
     pyo3_crate_path: &PyO3CratePath,
     ident: &Ident,
     name: &str,
+    is_final: bool,
 ) -> TokenStream {
-    IntrospectionNode::Map(
-        [
-            ("type", IntrospectionNode::String("class".into())),
-            (
-                "id",
-                IntrospectionNode::IntrospectionId(Some(ident_to_type(ident))),
-            ),
-            ("name", IntrospectionNode::String(name.into())),
-        ]
-        .into(),
-    )
-    .emit(pyo3_crate_path)
+    let mut desc = HashMap::from([
+        ("type", IntrospectionNode::String("class".into())),
+        (
+            "id",
+            IntrospectionNode::IntrospectionId(Some(ident_to_type(ident))),
+        ),
+        ("name", IntrospectionNode::String(name.into())),
+    ]);
+    if is_final {
+        desc.insert(
+            "decorators",
+            IntrospectionNode::List(vec![IntrospectionNode::ConstantType(
+                PythonIdentifier::module_attr("typing", "final"),
+            )
+            .into()]),
+        );
+    }
+    IntrospectionNode::Map(desc).emit(pyo3_crate_path)
 }
 
 #[expect(clippy::too_many_arguments)]
diff --git a/pyo3-macros-backend/src/pyclass.rs b/pyo3-macros-backend/src/pyclass.rs
index 8e6f1cebf77..2d37d3cec7b 100644
--- a/pyo3-macros-backend/src/pyclass.rs
+++ b/pyo3-macros-backend/src/pyclass.rs
@@ -2683,7 +2683,12 @@ impl<'a> PyClassImplsBuilder<'a> {
         let Ctx { pyo3_path, .. } = ctx;
         let name = get_class_python_name(self.cls, self.attr).to_string();
         let ident = self.cls;
-        let static_introspection = class_introspection_code(pyo3_path, ident, &name);
+        let static_introspection = class_introspection_code(
+            pyo3_path,
+            ident,
+            &name,
+            self.attr.options.subclass.is_none(),
+        );
         let introspection_id = introspection_id_const();
         quote! {
             #static_introspection
diff --git a/pytests/src/lib.rs b/pytests/src/lib.rs
index 26a33f81cab..60cb741adeb 100644
--- a/pytests/src/lib.rs
+++ b/pytests/src/lib.rs
@@ -25,7 +25,7 @@ mod pyo3_pytests {
     #[pymodule_export]
     use {
         comparisons::comparisons, consts::consts, enums::enums, pyclasses::pyclasses,
-        pyfunctions::pyfunctions,
+        pyfunctions::pyfunctions, subclassing::subclassing,
     };
 
     // Inserting to sys.modules allows importing submodules nicely from Python
@@ -43,7 +43,6 @@ mod pyo3_pytests {
         m.add_wrapped(wrap_pymodule!(othermod::othermod))?;
         m.add_wrapped(wrap_pymodule!(path::path))?;
         m.add_wrapped(wrap_pymodule!(sequence::sequence))?;
-        m.add_wrapped(wrap_pymodule!(subclassing::subclassing))?;
 
         // Inserting to sys.modules allows importing submodules nicely from Python
         // e.g. import pyo3_pytests.buf_and_str as bas
diff --git a/pytests/src/subclassing.rs b/pytests/src/subclassing.rs
index 8e451cd9183..ab3f2a6786f 100644
--- a/pytests/src/subclassing.rs
+++ b/pytests/src/subclassing.rs
@@ -2,23 +2,22 @@
 
 use pyo3::prelude::*;
 
-#[pyclass(subclass)]
-pub struct Subclassable {}
+#[pymodule(gil_used = false)]
+pub mod subclassing {
+    use pyo3::prelude::*;
 
-#[pymethods]
-impl Subclassable {
-    #[new]
-    fn new() -> Self {
-        Subclassable {}
-    }
+    #[pyclass(subclass)]
+    pub struct Subclassable {}
 
-    fn __str__(&self) -> &'static str {
-        "Subclassable"
-    }
-}
+    #[pymethods]
+    impl Subclassable {
+        #[new]
+        fn new() -> Self {
+            Subclassable {}
+        }
 
-#[pymodule]
-pub fn subclassing(m: &Bound<'_, PyModule>) -> PyResult<()> {
-    m.add_class::<Subclassable>()?;
-    Ok(())
+        fn __str__(&self) -> &'static str {
+            "Subclassable"
+        }
+    }
 }
diff --git a/pytests/stubs/comparisons.pyi b/pytests/stubs/comparisons.pyi
index 7287dea5d7c..77ea05a5123 100644
--- a/pytests/stubs/comparisons.pyi
+++ b/pytests/stubs/comparisons.pyi
@@ -1,17 +1,23 @@
+from typing import final
+
+@final
 class Eq:
     def __eq__(self, /, other: Eq) -> bool: ...
     def __ne__(self, /, other: Eq) -> bool: ...
     def __new__(cls, /, value: int) -> Eq: ...
 
+@final
 class EqDefaultNe:
     def __eq__(self, /, other: EqDefaultNe) -> bool: ...
     def __new__(cls, /, value: int) -> EqDefaultNe: ...
 
+@final
 class EqDerived:
     def __eq__(self, /, other: EqDerived) -> bool: ...
     def __ne__(self, /, other: EqDerived) -> bool: ...
     def __new__(cls, /, value: int) -> EqDerived: ...
 
+@final
 class Ordered:
     def __eq__(self, /, other: Ordered) -> bool: ...
     def __ge__(self, /, other: Ordered) -> bool: ...
@@ -21,6 +27,7 @@ class Ordered:
     def __ne__(self, /, other: Ordered) -> bool: ...
     def __new__(cls, /, value: int) -> Ordered: ...
 
+@final
 class OrderedDefaultNe:
     def __eq__(self, /, other: OrderedDefaultNe) -> bool: ...
     def __ge__(self, /, other: OrderedDefaultNe) -> bool: ...
@@ -29,6 +36,7 @@ class OrderedDefaultNe:
     def __lt__(self, /, other: OrderedDefaultNe) -> bool: ...
     def __new__(cls, /, value: int) -> OrderedDefaultNe: ...
 
+@final
 class OrderedDerived:
     def __eq__(self, /, other: OrderedDerived) -> bool: ...
     def __ge__(self, /, other: OrderedDerived) -> bool: ...
@@ -40,6 +48,7 @@ class OrderedDerived:
     def __new__(cls, /, value: int) -> OrderedDerived: ...
     def __str__(self, /) -> str: ...
 
+@final
 class OrderedRichCmp:
     def __eq__(self, /, other: OrderedRichCmp) -> bool: ...
     def __ge__(self, /, other: OrderedRichCmp) -> bool: ...
diff --git a/pytests/stubs/consts.pyi b/pytests/stubs/consts.pyi
index 66b0672c8a5..dfff3973371 100644
--- a/pytests/stubs/consts.pyi
+++ b/pytests/stubs/consts.pyi
@@ -1,7 +1,8 @@
-from typing import Final
+from typing import Final, final
 
 PI: Final[float]
 SIMPLE: Final = "SIMPLE"
 
+@final
 class ClassWithConst:
     INSTANCE: Final[ClassWithConst]
diff --git a/pytests/stubs/enums.pyi b/pytests/stubs/enums.pyi
index 95eaabac451..ec43dca52f8 100644
--- a/pytests/stubs/enums.pyi
+++ b/pytests/stubs/enums.pyi
@@ -1,6 +1,9 @@
+from typing import final
+
 class ComplexEnum: ...
 class MixedComplexEnum: ...
 
+@final
 class SimpleEnum:
     def __eq__(self, /, other: SimpleEnum | int) -> bool: ...
     def __ne__(self, /, other: SimpleEnum | int) -> bool: ...
diff --git a/pytests/stubs/pyclasses.pyi b/pytests/stubs/pyclasses.pyi
index c89ca836b4f..7aba82f4dfa 100644
--- a/pytests/stubs/pyclasses.pyi
+++ b/pytests/stubs/pyclasses.pyi
@@ -1,9 +1,10 @@
 from _typeshed import Incomplete
-from typing import Any
+from typing import Any, final
 
 class AssertingBaseClass:
     def __new__(cls, /, expected_type: Any) -> AssertingBaseClass: ...
 
+@final
 class ClassWithDecorators:
     def __new__(cls, /) -> ClassWithDecorators: ...
     @property
@@ -18,16 +19,20 @@ class ClassWithDecorators:
     @staticmethod
     def static_method() -> int: ...
 
+@final
 class ClassWithDict:
     def __new__(cls, /) -> ClassWithDict: ...
 
+@final
 class ClassWithoutConstructor: ...
 
+@final
 class EmptyClass:
     def __len__(self, /) -> int: ...
     def __new__(cls, /) -> EmptyClass: ...
     def method(self, /) -> None: ...
 
+@final
 class PlainObject:
     @property
     def bar(self, /) -> int: ...
@@ -38,10 +43,12 @@ class PlainObject:
     @foo.setter
     def foo(self, /, value: str) -> None: ...
 
+@final
 class PyClassIter:
     def __new__(cls, /) -> PyClassIter: ...
     def __next__(self, /) -> int: ...
 
+@final
 class PyClassThreadIter:
     def __new__(cls, /) -> PyClassThreadIter: ...
     def __next__(self, /) -> int: ...
diff --git a/pytests/stubs/subclassing.pyi b/pytests/stubs/subclassing.pyi
new file mode 100644
index 00000000000..80f512ca014
--- /dev/null
+++ b/pytests/stubs/subclassing.pyi
@@ -0,0 +1,3 @@
+class Subclassable:
+    def __new__(cls, /) -> Subclassable: ...
+    def __str__(self, /) -> str: ...