diff --git a/modules/distro/panelizer/CHANGELOG.txt b/modules/distro/panelizer/CHANGELOG.txt
index 8e9ae484b..f06a8db9e 100644
--- a/modules/distro/panelizer/CHANGELOG.txt
+++ b/modules/distro/panelizer/CHANGELOG.txt
@@ -1,3 +1,10 @@
+Panelizer 8.x-4.5, 2023-10-10
+-----------------------------
+#3288958 by Project Update Bot, DamienMcKenna: Drupal 10 compatibility fixes.
+#3352704 by sker101, codebymikey, hamzadwaya, Mingsong, joseph.olstad, jan
+  kellermann, DamienMcKenna: Additional Drupal 10 compatibility fixes.
+
+
 Panelizer 8.x-4.x-dev, xxxx-xx-xx
 ---------------------------------
 #2889815 by samuel.mortenson: Fix tests for Panelizer 8.x.
@@ -9,7 +16,6 @@ Panelizer 8.x-4.x-dev, xxxx-xx-xx
 #2912622 by gaydabura: Panelizer field should only show enabled view modes.
 #2878095 by zuernBernhard: Panelizer Post Update fails in combination with
   search_api index tracking.
-#3288958 by Project Update Bot, DamienMcKenna: Drupal 10 compatibility fixes.
 
 
 Panelizer 8.x-4.0, 2017-04-28
diff --git a/modules/distro/panelizer/js/panelizer-default-form.js b/modules/distro/panelizer/js/panelizer-default-form.js
index 76aafe84a..06474bf47 100644
--- a/modules/distro/panelizer/js/panelizer-default-form.js
+++ b/modules/distro/panelizer/js/panelizer-default-form.js
@@ -2,11 +2,14 @@
  * @file
  * Javascript for the Panelizer defaults page.
  */
-(function ($) {
+(function ($, once) {
   Drupal.behaviors.panelizer_default_form = {
     attach: function (context, settings) {
-      var $panelizer_checkbox = $(':input[name="panelizer[enable]"]');
+      var $panelizer_checkbox = $(once('panelizer-default-form', 'input[name="panelizer[enable]"]', context));
 
+      if (!$panelizer_checkbox.length) {
+        return;
+      }
       function update_form() {
         var $core_form = $('#field-display-overview-wrapper');
         if ($panelizer_checkbox.is(':checked')) {
@@ -17,8 +20,8 @@
         }
       }
 
-      $panelizer_checkbox.once('panelizer-default-form').click(update_form);
+      $panelizer_checkbox.click(update_form);
       update_form();
     }
   };
-})(jQuery);
+})(jQuery, once);
diff --git a/modules/distro/panelizer/panelizer.info.yml b/modules/distro/panelizer/panelizer.info.yml
index f9cf276e4..fe2c315f4 100644
--- a/modules/distro/panelizer/panelizer.info.yml
+++ b/modules/distro/panelizer/panelizer.info.yml
@@ -10,7 +10,7 @@ dependencies:
   - panels:panels
   - panels:panels_ipe
 
-# Information added by Drupal.org packaging script on 2022-08-23
-version: '8.x-4.4+2-dev'
+# Information added by Drupal.org packaging script on 2023-10-10
+version: '8.x-4.5'
 project: 'panelizer'
-datestamp: 1661286213
+datestamp: 1696975733
diff --git a/modules/distro/panelizer/panelizer.install b/modules/distro/panelizer/panelizer.install
index ba3925d61..5515f62f6 100644
--- a/modules/distro/panelizer/panelizer.install
+++ b/modules/distro/panelizer/panelizer.install
@@ -10,7 +10,7 @@
  * default layouts.
  */
 function panelizer_update_8401(&$sandbox) {
-  module_load_install('panels');
+  \Drupal::moduleHandler()->loadInclude('panels', 'install');
   $config_factory = \Drupal::configFactory();
   foreach ($config_factory->listAll('core.entity_view_display.') as $entity_display_name) {
     $entity_display = $config_factory->getEditable($entity_display_name);
diff --git a/modules/distro/panelizer/panelizer.libraries.yml b/modules/distro/panelizer/panelizer.libraries.yml
index 50b9c7622..45d8908c2 100644
--- a/modules/distro/panelizer/panelizer.libraries.yml
+++ b/modules/distro/panelizer/panelizer.libraries.yml
@@ -4,7 +4,7 @@ panelizer_default_form:
     js/panelizer-default-form.js: {}
   dependencies:
     - core/jquery
-    - core/jquery.once
+    - core/once
 panels_ipe:
   version: VERSION
   js:
diff --git a/modules/distro/panelizer/panelizer.module b/modules/distro/panelizer/panelizer.module
index badc90dc0..88c11eb6b 100644
--- a/modules/distro/panelizer/panelizer.module
+++ b/modules/distro/panelizer/panelizer.module
@@ -343,7 +343,7 @@ function template_preprocess_panelizer_wizard_tree(&$variables) {
   /** @var $wizard \Drupal\ctools\Wizard\FormWizardInterface|\Drupal\ctools\Wizard\EntityFormWizardInterface */
   $wizard = $variables['wizard'];
   $cached_values = $variables['cached_values'];
-  $tree = $variables['tree'];
+  $tree = $variables['tree'] ?: [];
   $variables['step'] = $wizard->getStep($cached_values);
 
   foreach ($wizard->getOperations($cached_values) as $step => $operation) {
diff --git a/modules/distro/panelizer/panelizer.post_update.php b/modules/distro/panelizer/panelizer.post_update.php
index fcb8e184e..a5b4aee56 100644
--- a/modules/distro/panelizer/panelizer.post_update.php
+++ b/modules/distro/panelizer/panelizer.post_update.php
@@ -19,7 +19,7 @@
  * default layouts.
  */
 function panelizer_post_update_rename_layout_machine_names(&$sandbox) {
-  module_load_install('panels');
+  \Drupal::moduleHandler()->loadInclude('panels', 'install');
 
   /** @var \Drupal\panelizer\Plugin\PanelizerEntityManager $panelizer_manager */
   $panelizer_manager = \Drupal::service('plugin.manager.panelizer_entity');
@@ -31,6 +31,7 @@ function panelizer_post_update_rename_layout_machine_names(&$sandbox) {
       $storage = \Drupal::entityTypeManager()->getStorage($entity_type);
       $ids = $storage->getQuery()
         ->condition('panelizer', serialize([]), '<>')
+        ->accessCheck(FALSE)
         ->execute();
 
       foreach ($storage->loadMultiple($ids) as $entity_id => $entity) {
diff --git a/modules/distro/panelizer/panelizer_quickedit/panelizer_quickedit.info.yml b/modules/distro/panelizer/panelizer_quickedit/panelizer_quickedit.info.yml
index 1be832157..00584941a 100644
--- a/modules/distro/panelizer/panelizer_quickedit/panelizer_quickedit.info.yml
+++ b/modules/distro/panelizer/panelizer_quickedit/panelizer_quickedit.info.yml
@@ -8,7 +8,7 @@ dependencies:
   - panelizer:panelizer
   - drupal:quickedit
 
-# Information added by Drupal.org packaging script on 2022-08-23
-version: '8.x-4.4+2-dev'
+# Information added by Drupal.org packaging script on 2023-10-10
+version: '8.x-4.5'
 project: 'panelizer'
-datestamp: 1661286213
+datestamp: 1696975733
diff --git a/modules/distro/panelizer/src/Panelizer.php b/modules/distro/panelizer/src/Panelizer.php
index d34b8de10..1aaefc032 100644
--- a/modules/distro/panelizer/src/Panelizer.php
+++ b/modules/distro/panelizer/src/Panelizer.php
@@ -171,6 +171,7 @@ public function getEntityViewDisplay($entity_type_id, $bundle, $view_mode) {
     $results = \Drupal::entityQuery('entity_view_display')
       ->condition('id', $candidate_ids)
       ->condition('status', TRUE)
+      ->accessCheck()
       ->execute();
 
     // Select the first valid candidate display, if any.
diff --git a/modules/distro/panelizer/tests/modules/panelizer_test/panelizer_test.info.yml b/modules/distro/panelizer/tests/modules/panelizer_test/panelizer_test.info.yml
index bc0c22784..69e6a4d21 100644
--- a/modules/distro/panelizer/tests/modules/panelizer_test/panelizer_test.info.yml
+++ b/modules/distro/panelizer/tests/modules/panelizer_test/panelizer_test.info.yml
@@ -1,11 +1,11 @@
 type: module
 name: Panelizer Test
 description: 'Required for Panelizer simpletests only.'
-core_version_requirement: ^8.8 || ^9
+core_version_requirement: ^8.8 || ^9 || ^10
 dependencies:
   - panelizer:panelizer
 
-# Information added by Drupal.org packaging script on 2022-08-23
-version: '8.x-4.4+2-dev'
+# Information added by Drupal.org packaging script on 2023-10-10
+version: '8.x-4.5'
 project: 'panelizer'
-datestamp: 1661286213
+datestamp: 1696975733
diff --git a/modules/distro/panelizer/tests/src/Functional/PanelizerDefaultsTest.php b/modules/distro/panelizer/tests/src/Functional/PanelizerDefaultsTest.php
index 33878cbaa..08122e86f 100644
--- a/modules/distro/panelizer/tests/src/Functional/PanelizerDefaultsTest.php
+++ b/modules/distro/panelizer/tests/src/Functional/PanelizerDefaultsTest.php
@@ -16,7 +16,7 @@ class PanelizerDefaultsTest extends BrowserTestBase {
   /**
    * {@inheritdoc}
    */
-  protected $defaultTheme = 'bartik';
+  protected $defaultTheme = 'stark';
 
   /**
    * {@inheritdoc}
@@ -71,7 +71,7 @@ public function test() {
       // default, they aren't.
       $this->drupalGet('node/add/page');
       $this->assertSession()->statusCodeEquals(200);
-      $this->assertSession()->fieldValueNotEquals("panelizer['{$i}][default]", '');
+      $this->assertSession()->fieldNotExists("panelizer['{$i}][default]");
       // Allow user to select panelized modes in UI.
       $this->panelize('page', $view_mode_name, [
         'panelizer[custom]' => TRUE,
diff --git a/modules/distro/panelizer/tests/src/Functional/PanelizerIpeTest.php b/modules/distro/panelizer/tests/src/Functional/PanelizerIpeTest.php
index 731ff6c97..1e1268bb0 100644
--- a/modules/distro/panelizer/tests/src/Functional/PanelizerIpeTest.php
+++ b/modules/distro/panelizer/tests/src/Functional/PanelizerIpeTest.php
@@ -86,7 +86,7 @@ protected function createAdminUser(array $perms = array()) {
       // From Panels.
       'access panels in-place editing',
     ];
-    $this->verbose('<pre>' . print_r($perms, TRUE) . '</pre>');
+    dump('<pre>' . print_r($perms, TRUE) . '</pre>');
     return $this->drupalCreateUser($perms);
   }
 
@@ -111,7 +111,7 @@ public function testAdminUser() {
     $matches = [];
     if (preg_match('@<script type="application/json" data-drupal-selector="drupal-settings-json">([^<]*)</script>@', $this->getSession()->getPage()->getContent(), $matches)) {
       $drupalSettings = Json::decode($matches[1]);
-      $this->verbose('<pre>' . print_r($drupalSettings, TRUE) . '</pre>');
+      dump('<pre>' . print_r($drupalSettings, TRUE) . '</pre>');
     }
     $this->assertNotNull($drupalSettings);
     if (!empty($drupalSettings)) {
@@ -158,7 +158,7 @@ public function testAdministerPanelizerPermission() {
     $matches = [];
     if (preg_match('@<script type="application/json" data-drupal-selector="drupal-settings-json">([^<]*)</script>@', $this->getSession()->getPage()->getContent(), $matches)) {
       $drupalSettings = Json::decode($matches[1]);
-      $this->verbose('<pre>' . print_r($drupalSettings, TRUE) . '</pre>');
+      dump('<pre>' . print_r($drupalSettings, TRUE) . '</pre>');
     }
     $this->assertNotNull($drupalSettings);
     if (!empty($drupalSettings)) {
@@ -375,7 +375,7 @@ protected function setupPermissionTests(array $perms, $node = NULL) {
     $matches = [];
     if (preg_match('@<script type="application/json" data-drupal-selector="drupal-settings-json">([^<]*)</script>@', $this->getSession()->getPage()->getContent(), $matches)) {
       $drupalSettings = Json::decode($matches[1]);
-      $this->verbose('<pre>' . print_r($drupalSettings, TRUE) . '</pre>');
+      dump('<pre>' . print_r($drupalSettings, TRUE) . '</pre>');
     }
     return $drupalSettings;
   }
diff --git a/modules/distro/panelizer/tests/src/Functional/PanelizerNodeFunctionalTest.php b/modules/distro/panelizer/tests/src/Functional/PanelizerNodeFunctionalTest.php
index 827bd9a95..5fb98d3ca 100644
--- a/modules/distro/panelizer/tests/src/Functional/PanelizerNodeFunctionalTest.php
+++ b/modules/distro/panelizer/tests/src/Functional/PanelizerNodeFunctionalTest.php
@@ -151,7 +151,7 @@ public function testPanelizerDefault() {
     $node = $this->drupalCreateNode(['type' => 'page']);
     $out = $this->drupalGet('node/' . $node->id());
     $this->assertSession()->statusCodeEquals(200);
-    $this->verbose($out);
+    dump($out);
     $elements = $this->xpath('//*[@id="panels-ipe-content"]');
     if (is_array($elements)) {
       $this->assertSame(count($elements), 1);
diff --git a/modules/distro/panelizer/tests/src/Functional/PanelizerNodeTranslationsTest.php b/modules/distro/panelizer/tests/src/Functional/PanelizerNodeTranslationsTest.php
index 2952f2187..01b75d1e0 100644
--- a/modules/distro/panelizer/tests/src/Functional/PanelizerNodeTranslationsTest.php
+++ b/modules/distro/panelizer/tests/src/Functional/PanelizerNodeTranslationsTest.php
@@ -174,7 +174,7 @@ public function testPanelizerDefault() {
     ]);
     $out = $this->drupalGet('node/' . $node->id());
     $this->assertSession()->statusCodeEquals(200);
-    $this->verbose($out);
+    dump($out);
     $elements = $this->xpath('//*[@id="panels-ipe-content"]');
     if (is_array($elements)) {
       $this->assertSame(count($elements), 1);
diff --git a/modules/distro/panelizer/tests/src/Functional/PanelizerTermFunctionalTest.php b/modules/distro/panelizer/tests/src/Functional/PanelizerTermFunctionalTest.php
index 5469be531..69a2829fc 100644
--- a/modules/distro/panelizer/tests/src/Functional/PanelizerTermFunctionalTest.php
+++ b/modules/distro/panelizer/tests/src/Functional/PanelizerTermFunctionalTest.php
@@ -93,7 +93,7 @@ public function testPanelizerDefault() {
 
     $out = $this->drupalGet('taxonomy/term/' . $term->id());
     $this->assertSession()->statusCodeEquals(200);
-    $this->verbose($out);
+    dump($out);
     $elements = $this->xpath('//*[@id="panels-ipe-content"]');
     if (is_array($elements)) {
       $this->assertSame(count($elements), 1);
diff --git a/modules/distro/panelizer/tests/src/Functional/PanelizerTestTrait.php b/modules/distro/panelizer/tests/src/Functional/PanelizerTestTrait.php
index a5e47ea6f..9ef589992 100644
--- a/modules/distro/panelizer/tests/src/Functional/PanelizerTestTrait.php
+++ b/modules/distro/panelizer/tests/src/Functional/PanelizerTestTrait.php
@@ -2,6 +2,7 @@
 
 namespace Drupal\Tests\panelizer\Functional;
 
+use Drupal\Core\Url;
 use Drupal\user\Entity\User;
 
 /**
@@ -74,24 +75,27 @@ protected function createTestNode($type = 'page') {
    *   (optional) Additional form values.
    */
   protected function panelize($content_type = 'page', $display = NULL, array $values = []) {
+    /** @var \Drupal\Tests\WebAssert $assert_sesion */
+    $assert_session = $this->assertSession();
+
     $this->drupalGet("admin/structure/types");
-    $this->assertResponse(200);
+    $assert_session->statusCodeEquals(200);
 
     $this->drupalGet("admin/structure/types/manage/{$content_type}");
-    $this->assertResponse(200);
+    $assert_session->statusCodeEquals(200);
 
     $path = "admin/structure/types/manage/{$content_type}/display";
     if (!empty($display)) {
       $path .= '/' . $display;
     }
     $this->drupalGet($path);
-    $this->assertResponse(200);
+    $assert_session->statusCodeEquals(200);
 
     $edit = [
       'panelizer[enable]' => TRUE,
     ] + $values;
-    $this->drupalPostForm(NULL, $edit, t('Save'));
-    $this->assertResponse(200);
+    $this->submitForm($edit, t('Save'));
+    $assert_session->statusCodeEquals(200);
 
     \Drupal::service('entity_display.repository')->getFormDisplay('node', $content_type, 'default')
       ->setComponent('panelizer', [
@@ -114,14 +118,17 @@ protected function panelize($content_type = 'page', $display = NULL, array $valu
    *   (optional) Additional form values.
    */
   protected function unpanelize($content_type = 'page', $display = NULL, array $values = []) {
+    /** @var \Drupal\Tests\WebAssert $assert_sesion */
+    $assert_session = $this->assertSession();
+
     $this->drupalGet("admin/structure/types/manage/{$content_type}/display/{$display}");
-    $this->assertResponse(200);
+    $assert_session->statusCodeEquals(200);
 
     $edit = [
       'panelizer[enable]' => FALSE,
     ] + $values;
-    $this->drupalPostForm(NULL, $edit, t('Save'));
-    $this->assertResponse(200);
+    $this->submitForm($edit, t('Save'));
+    $assert_session->statusCodeEquals(200);
 
     \Drupal::service('entity_display.repository')->getFormDisplay('node', $content_type, 'default')
       ->removeComponent('panelizer')
@@ -136,6 +143,9 @@ protected function unpanelize($content_type = 'page', $display = NULL, array $va
    *  'page'.
    */
   protected function addPanelizerDefault($content_type = 'page', $display = 'default') {
+    /** @var \Drupal\Tests\WebAssert $assert_sesion */
+    $assert_session = $this->assertSession();
+
     $label = $this->getRandomGenerator()->word(16);
     $id = strtolower($label);
     $default_id = "node__{$content_type}__{$display}__{$id}";
@@ -149,7 +159,7 @@ protected function addPanelizerDefault($content_type = 'page', $display = 'defau
       $path .= '/' . $display;
     }
     $this->drupalGet($path);
-    $this->assertResponse(200);
+    $assert_session->statusCodeEquals(200);
     $this->clickLink('Add a new Panelizer default display');
 
     // Step 1: Enter the default's label and ID.
@@ -157,18 +167,19 @@ protected function addPanelizerDefault($content_type = 'page', $display = 'defau
       'id' => $id,
       'label' => $label,
     ];
-    $this->drupalPostForm(NULL, $edit, t('Next'));
-    $this->assertResponse(200);
+    $this->submitForm($edit, t('Next'));
+    $assert_session->statusCodeEquals(200);
 
     // Step 2: Define contexts.
-    $this->assertUrl("admin/structure/panelizer/add/{$default_id}/contexts", $options);
-    $this->drupalPostForm(NULL, [], t('Next'));
-    $this->assertResponse(200);
+
+    $assert_session->addressEquals(Url::fromUserInput("/admin/structure/panelizer/add/{$default_id}/contexts", $options)->toString());
+    $this->submitForm([], t('Next'));
+    $assert_session->statusCodeEquals(200);
 
     // Step 3: Select layout.
-    $this->assertUrl("admin/structure/panelizer/add/{$default_id}/layout", $options);
-    $this->drupalPostForm(NULL, [], t('Next'));
-    $this->assertResponse(200);
+    $assert_session->addressEquals(Url::fromUserInput("/admin/structure/panelizer/add/{$default_id}/layout", $options)->toString());
+    $this->submitForm([], t('Next'));
+    $assert_session->statusCodeEquals(200);
 
     // Step 4: If the layout has settings (new since Drupal 8.8), accept the
     // defaults.
@@ -180,9 +191,9 @@ protected function addPanelizerDefault($content_type = 'page', $display = 'defau
     }
 
     // Step 5: Select content.
-    $this->assertUrl("admin/structure/panelizer/add/{$default_id}/content", $options);
-    $this->drupalPostForm(NULL, [], t('Finish'));
-    $this->assertResponse(200);
+    $assert_session->addressEquals(Url::fromUserInput("/admin/structure/panelizer/add/{$default_id}/content", $options)->toString());
+    $this->submitForm([], t('Finish'));
+    $assert_session->statusCodeEquals(200);
 
     return $id;
   }
@@ -199,10 +210,13 @@ protected function addPanelizerDefault($content_type = 'page', $display = 'defau
    *   (optional) The default ID.
    */
   protected function deletePanelizerDefault($content_type = 'page', $display = 'default', $id = 'default') {
+    /** @var \Drupal\Tests\WebAssert $assert_sesion */
+    $assert_session = $this->assertSession();
+
     $this->drupalGet("admin/structure/panelizer/delete/node__{$content_type}__{$display}__{$id}");
-    $this->assertResponse(200);
-    $this->drupalPostForm(NULL, [], t('Confirm'));
-    $this->assertResponse(200);
+    $assert_session->statusCodeEquals(200);
+    $this->submitForm([], t('Confirm'));
+    $assert_session->statusCodeEquals(200);
   }
 
   /**
diff --git a/modules/distro/panelizer/tests/src/Functional/PanelizerUserFunctionalTest.php b/modules/distro/panelizer/tests/src/Functional/PanelizerUserFunctionalTest.php
index 40e57991a..a5494d953 100644
--- a/modules/distro/panelizer/tests/src/Functional/PanelizerUserFunctionalTest.php
+++ b/modules/distro/panelizer/tests/src/Functional/PanelizerUserFunctionalTest.php
@@ -97,7 +97,7 @@ public function testPanelizerDefault() {
     // Check the user entity page.
     $out = $this->drupalGet('user/' . $account->id());
     $this->assertSession()->statusCodeEquals(200);
-    $this->verbose($out);
+    dump($out);
 
     // Verify that
     $elements = $this->xpath('//*[@id="panels-ipe-content"]');
diff --git a/modules/distro/panelizer/tests/src/Functional/Update/PanelizerLayoutIDUpdateTest.php b/modules/distro/panelizer/tests/src/Functional/Update/PanelizerLayoutIDUpdateTest.php
index d7fd728f1..8e57090b2 100644
--- a/modules/distro/panelizer/tests/src/Functional/Update/PanelizerLayoutIDUpdateTest.php
+++ b/modules/distro/panelizer/tests/src/Functional/Update/PanelizerLayoutIDUpdateTest.php
@@ -16,7 +16,7 @@ class PanelizerLayoutIDUpdateTest extends UpdatePathTestBase {
    */
   protected function setDatabaseDumpFiles() {
     $this->databaseDumpFiles = [
-      $this->getDrupalRoot() . '/core/modules/system/tests/fixtures/update/drupal-8.8.0.bare.standard.php.gz',
+      $this->getDrupalRoot() . '/core/modules/system/tests/fixtures/update/drupal-9.4.0.bare.standard.php.gz',
       __DIR__ . '/../../../fixtures/update/drupal-8.8.panelizer.minimal.php.gz',
     ];
   }
diff --git a/modules/distro/panelizer/tests/src/FunctionalJavascript/PanelizerIntegrationTest.php b/modules/distro/panelizer/tests/src/FunctionalJavascript/PanelizerIntegrationTest.php
index 2a2b38911..fc8f4468f 100644
--- a/modules/distro/panelizer/tests/src/FunctionalJavascript/PanelizerIntegrationTest.php
+++ b/modules/distro/panelizer/tests/src/FunctionalJavascript/PanelizerIntegrationTest.php
@@ -52,10 +52,9 @@ protected function setUp(): void {
       'access content',
       'access panels in-place editing',
       'administer blocks',
-      'administer content types',
-      'administer nodes',
       'administer node display',
       'administer panelizer',
+      'bypass node access',
     ]);
     $this->drupalLogin($admin_user);