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An example Jupyter Notebook for calculating partial charges using Psi4

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CalculatePartialChargesWithPsi4

An example Jupyter Notebook for calculating partial charges using Psi4.

The program is written in Python 3.7 requiring the following Python libraries:

  • RDKit
  • RESP
  • Psi4
  • OpenBabel

It takes a sdf file with compounds (incl 3D coordinates) and outputs a mol2 file with RESP derived partial charges. Options for setting method (HF, B3LYP, ...), basis set (3-21G*, 6-31G**) and singlepoint or geometry optimization.

Contact: dr.jonas.bostrom at gmail.com

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An example Jupyter Notebook for calculating partial charges using Psi4

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