This dataset consists of (11-c) UCB-J PET and T1 Weighted (MPnRAGE_VFA : motion corrected) images. The cohort includes adults who are 60 years and above with a variety of clinical cognitive diagnoses including Alzheimer's Dementia, Mild Cognitive Impairment, and Normal cognition. All images are provided in native imaging space and have not been co-registered to a common space.
The resolution is 1mm isotropic. The aquisition parameters are as follows: "EchoTime": 0.00182, "RepetitionTime": 0.004876, "FlipAngle": 4, "ShimSetting": [ 8, 12, -37]
These two seminal papers describe the theory and methodology of the T1-weighted MPnRAGE sequence: https://pmc.ncbi.nlm.nih.gov/articles/PMC6192848/ and https://pmc.ncbi.nlm.nih.gov/articles/PMC8525331/#R13
A target dose of 5-15 mCi +/- 10% of UCB-J bolus is injected over ~30 second infusion with the participant positioned in the scanner. A 70 minute dynamic PET scan was initiated with the injection of radiotracer.