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lucaspalmeira/README.md

Hi there, I'm Lucas! 👋

About Me

I am currently pursuing a Master's degree in Bioinformatics at the Federal University of Minas Gerais (UFMG), Brazil.

I am the developer of FUNIN, a web platform designed to organize and provide access to GH32 fungal enzyme data. The system was built with Python, Flask, MongoDB, and Docker, and serves as a foundational dataset for future AI-driven enzyme design.

Currently, my research focuses on the optimization of GH32 fungal enzymes derived from the FUNIN database, using Protein Language Models (pLMs) and deep learning frameworks such as PyTorch and TensorFlow.

My research interests include Protein Language Models (pLMs), Large Language Models (LLMs), Machine Learning, Genetic Algorithms, and Protein Design & Engineering.

Featured Projects

Tech stack: Python • Flask • MongoDB • Docker FUNIN is a web application designed to catalog and visualize GH32 fungal inulinases relevant to bioethanol production. It integrates curated enzymatic and sequence data to support AI-based enzyme engineering.

Publication: DOI: 10.1016/j.ijbiomac.2025.145050


Tech stack: Python • Docker • MongoDB • CLEAN (Enzyme function prediction using contrastive learning) A comprehensive ELT (Extract, Load, Transform) workflow that extracts data from InterPro and UniProt databases to build the FUNIN database. The pipeline integrates multiple data sources and implements enzyme function prediction using contrastive learning approaches for comprehensive enzyme characterization.


SAGAPEP — Predictive Pipeline for Antimicrobial Peptides

Tech stack: Python • Scikit-learn A predictive software for evaluating antimicrobial peptide activity against SARS-CoV-2.


Research

  • Current Focus: Optimization of fungal GH32 enzymes using ESM-based pLMs, genetic algorithms, and deep learning architectures for protein function prediction and engineering.

GitHub Stats


Languages & Tools

python logo git logo linux logo bash logo pandas logo jupyter logo Scikit-Learn logo docker logo flask logo fastapi logo mongodb logo html5 logo css logo

Structural Bioinformatics and Cheminformatics Tools


Connect with Me

LinkedIn

Pinned Loading

  1. gh32 gh32 Public

    Glycoside Hydrolase Family 32 Database

    Python

  2. AMPs AMPs Public

    Predictive (AI) Pipeline for the Bioactivity of Antimicrobial Peptides

    Python 1

  3. BioPep BioPep Public

    Search, molecular modeling and molecular docking of peptides.

    Python 8 4