MITE (Minimum Information about a Tailoring Enzyme) is a community-driven database for the characterization of tailoring enzymes. These enzymes play crucial roles in the biosynthesis of secondary or specialized metabolites, naturally occurring molecules with strong biological activities, such as antibiotic properties.
This repository manages auxiliary files for the MITE Webpage and is intended for internal use. Briefly, the code in this repository:
- Downloads the newest version of
mite_data - Generates the BLAST databases needed by MITE Web
- Generates the Jinja2-compatible mite JSON files (only if change is detected between current and previous version)
- Downloads
.pdbfiles from AlphaFoldDB matching the UniProt Accessions in the MITE data files - Generates visualizations of predicted protein structures
For more information, visit the MITE Data Standard Organization page or read our publication.
Update the auxiliary files (automatically updates to the newest version of mite_data).
Previous temporary dirs (data/data, data/fasta, data/pdb) need to be manually removed if they are to be newly downloaded.
docker build -t mite-cli .
docker run --rm -v $(pwd)/data:/data -u $(id -u):$(id -g) -e HOME=/tmp mite-cli
Already existing images will not be overwritten.
This repository is licensed under the MIT License
You can find additional citation information in the CITATION.cff file.