UNRAVEL: UN-biased high-Resolution Analysis and Validation of Ensembles using Light sheet images
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Updated
Dec 15, 2025 - Python
UNRAVEL: UN-biased high-Resolution Analysis and Validation of Ensembles using Light sheet images
This project builds machine learning models to automatically detect and classify protein complexes in cryo-electron tomography (cryoET) images, enabling scalable analysis of cellular structures and supporting advanced biological and medical research.
Automated detection of protein complexes in cryo-electron tomography (cryoET) data. ML models identify five particle classes using a weighted F-β (β=4) metric focused on recall, especially for hard targets, helping reveal cellular “dark matter” and advance biological discovery.
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